Search results for "THEORY [COSMOLOGY]"

Mitochondria, oxidative stress and aging

2000

In the eighties, Miquel and Fleming suggested that mitochondria play a key role in cellular aging. Mitochondria, and specially mitochondrial DNA (mtDNA), are major targets of free radical attack. At present, it is well established that mitochondrial deficits accumulate upon aging due to oxidative damage. Thus, oxidative lesions to mtDNA accumulate with age in human and rodent tissues. Furthermore, levels of oxidative damage to mtDNA are several times higher than those of nuclear DNA. Mitochondrial size increases whereas mitochondrial membrane potential decreases with age in brain and liver. Recently, we have shown that treatment with certain antioxidants, such as sulphur-containing antioxid…

Biomarkers of oxidative and nitrosative damage in Alzheimer's disease and mild cognitive impairment

2009

Alzheimer's disease (AD) is the most common type of dementia in the elderly. Products of oxidative and nitrosative stress (OS and NS, respectively) accumulate with aging, which is the main risk factor for AD. This provides the basis for the involvement of OS and NS in AD pathogenesis. OS and NS occur in biological systems due to the dysregulation of the redox balance, caused by a deficiency of antioxidants and/or the overproduction of free radicals. Free radical attack against lipids, proteins, sugars and nucleic acids leads to the formation of bioproducts whose detection in fluids and tissues represents the currently available method for assessing oxidative/nitrosative damage. Post-mortem …

Glutathione, oxidative stress and aging

1996

The free radical theory of aging proposes that the impairment in physiological performance associated with aging is caused by the detrimental effects of oxygen free radicals. This is interesting because it provides us with a theoretical framework to understand aging and because it suggests a rationale for intervention, i.e., antioxidant administration. Thus, the study of antioxidant systems of the cell may be very important in gerontological studies. Glutathione is one of the main nonprotein antioxidants in the cell which, together with its related enzymes, constitute the “glutathione system.” The involvement of glutathione in aging has been known since the early seventies. Several studies …

Trait Empathy associated with Agreeableness and rhythmic entrainment in a spontaneous movement to music task: Preliminary exploratory investigations

2017

The simulation theory of empathy suggests that we use motor processing to empathise, through modelling the actions of others. Similarly, research into embodied music cognition posits that music, particularly musical rhythm, is perceived as a motor stimulus. In both cases, the human Mirror Neuron System (MNS) is put forward as a potential underlying mechanism. If this is the case, some overlap may exist between the ability to empathise with others, and the ability to perceive rhythm in music. The present study investigated this relationship indirectly, through the study of individual differences in Trait Empathy and rhythmic entrainment. Undergraduate students ( N = 237) completed a questio…

Symmetric and asymmetric cryptographic key exchange protocols in the octonion algebra

2019

AbstractWe propose three cryptographic key exchange protocols in the octonion algebra. Using the totient function, defined for integral octonions, we generalize the RSA public-key cryptosystem to the octonion arithmetics. The two proposed symmetric cryptographic key exchange protocols are based on the automorphism and the derivation of the octonion algebra.

Computing the ℤ2-Cocharacter of 3 × 3 Matrices of Odd Degree

2013

Let F be a field of characteristic 0 and A = M 2, 1(F) the algebra of 3 × 3 matrices over F endowed with the only non trivial ℤ2-grading. Aver'yanov in [1] determined a set of generators for the T 2-ideal of graded identities of A. Here we study the identities in variables of homogeneous degree 1 via the representation theory of the symmetric group, and we determine the decomposition of the corresponding character into irreducibles.

Irreducible Representations of Periodic Finitary Linear Groups

1996

Geometric interpretation of the optimality conditions in multifacility location and applications

1991

Geometrical optimality conditions are developed for the minisum multifacility location problem involving any norm. These conditions are then used to derive sufficient conditions for coincidence of facilities at optimality; an example is given to show that these coincidence conditions seem difficult to generalize.

A remark on conjectures in modular representation theory

1987

On the representation theory of quantum Heisenberg group and algebra

1994

We show that the quantum Heisenberg groupH q (1) and its *-Hopf algebra structure can be obtained by means of contraction from quantumSU q (2) group. Its dual Hopf algebra is the quantum Heisenberg algebraU q (h(1)). We derive left and right regular representations forU q (h(1)) as acting on its dualH q (1). Imposing conditions on the right representation, the left representation is reduced to an irreducible holomorphic representation with an associated quantum coherent state. Realized in the Bargmann-Hilbert space of analytic functions the unitarity of regular representation is also shown. By duality, left and right regular representations for quantum Heisenberg group with the quantum Heis…